Nutraceutical Success Story

Challenge

A multi-vitamin tablet was presented to FreeThink to determine the amount of overage needed for each individual vitamin, to minimize cost while assuring quality.

 

FreeThink’s Approach

The following actives were studied: Vitamins B1, B12, A, C, K and Beta Carotene

 

Results/ASAPprime® Design

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The assay values were determined for each of the actives after storage (open), with all analyses done in a single batch.

ASAPprime® models were successfully developed for assay loss for each vitamin.  In each case, the model predictions were found to match prior long-term, in-packaging, data.  Below are the predictions for each vitamin (in packaging), which allowed the sponsor to determine the amount of overage needed based on the specifications for each vitamin.

 

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