Resources


Janssen: ASAP Concept and Case Study

November 21, 2016
#Customer Presentation/ Publications using ASAPprime®

Presentation by Dr. Thielges, Informa Life Sciences, 2013 (London) Click here to view presentation.

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GSK Consumer Health: Accelerated Stability Assessment Study for Nicorette® Lozenge

November 21, 2016
#Customer Presentation/ Publications using ASAPprime®

Poster by Dr. Chen, AAPS 2013 (San Antonio) Click here for a closer view

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Pfizer: Predicting the Long-Term Stability of Solid-State Pharmaceuticals

November 21, 2016
#Customer Presentation/ Publications using ASAPprime®

Presentation by Dr. Scrivens, 2015 (London)   Click here to view presentation.

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Accelerated Stability Modeling for Peptides: a Case Study with Bacitracin

November 21, 2016
#ASAPprime® and Stability Modeling

The Accelerated Stability Assessment Program (ASAP) was applied for the first time to a peptide, the antibiotic active pharmaceutical ingredient bacitracin. Bacitracin and its complex with zinc were exposed to temperature and relative humidity conditions from 50 to 80°C and from 0 to 63% for up to 21 days. High-performance liquid chromatography was used to […]

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ASAPprime® Concept and Case Studies Webinar

August 22, 2016
#Videos

Presentation by Dr. Sabine Thielges (Janssen Pharmaceuticals) from 29 January 2014

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Maximizing the Accuracy of ASAPprime® Predictions Webinar

August 22, 2016
#Videos

First presentation by Dr. Garry Scrivens (Pfizer Pharmaceuticals) describing how to use ASAPprime® predictions most effectively. Second presentation by Dr. Lilan Chen (GSK Consumer Health) about an ASAPprime® case study using Nicorette Lozenges. (Start time 32:30) 

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Impact of sertraline salt form on the oxidative stability in powder blends

August 22, 2016
#ASAPprime® and Stability Modeling

Click to access the full document

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A Scientific and Statistical Analysis of Accelerated Aging for Pharmaceuticals. Part 1: Accuracy of Fitting Methods

August 22, 2016

Three competing mathematical fitting models (a point-by-point estimation method, a linear fit method, and an isoconversion method) of chemical stability (related substance growth) when using high temperature data to predict room temperature shelf-life were employed in a detailed comparison. In each case, complex degradant formation behavior was analyzed by both exponential and linear forms of […]

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Lean Stability

August 22, 2016
#ASAPprime® and Stability Modeling

D. Volgan, J. Hofer, R. Timpano, K. Vukovinksy, K. Waterman and K. Norris, “Lean Stability” AAPS Newsmagazine Sept. 2015, 14-16. Click to access document

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A computational model for particle size influence on drug absorption during controlled-release colonic delivery

August 22, 2016

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