Why Work With FreeThink’s Formulation Team
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Formulation Development

ADAP: Accelerated Drug Advancement Process
Target Product Profile
Solubilization Development
Controlled Release Development
Stable Formulation Development

ADAP: Accelerated Drug Advancement Process
Target Product Profile
Solubilization Development
Controlled Release Development
Stable Formulation Development
Target Product Profile
FreeThink develops a project-specific Target Product Profile (TPP) with you to align on product musts and wants, identify gaps in current knowledge, and catalyze brainstorming. Our scientists have extensive experience in all stages of product development and understand which parameters are critical.
Solubilization Development
Controlled Release Development
FreeThink scientists identify suitable controlled release technologies based on the drug properties and the TPP. Oral extended release technologies include matrices, beads/multiparticulates, and osmotics. Our proprietary OzmoCAP® platform enables factors affecting extended release viability including gastrointestinal solubility, absorption, efflux, and metabolism to be rapidly assessed in canine studies. We have expertise in enteric and taste-masking options and can develop depot systems for long-acting injectables.
Stable Formulation Development
FreeThink can develop a stable formulation in less than eight weeks using a material-sparing process. We use a tiered formulation process which is faster and more accurate than traditional excipient compatibility methods. Our approach uses realistic full formulations rather than binary combinations. The stability assessment uses our ASAPprime® which quickly determines formulation viability, including packaging considerations.